Treatment of Canine Hemangiosarcoma: 2000 and Beyond
نویسندگان
چکیده
منابع مشابه
Actionable mutations in canine hemangiosarcoma
BACKGROUND Angiosarcomas (AS) are rare in humans, but they are a deadly subtype of soft tissue sarcoma. Discovery sequencing in AS, especially the visceral form, is hampered by the rarity of cases. Most diagnostic material exists as archival formalin fixed, paraffin embedded tissue which serves as a poor source of high quality DNA for genome-wide sequencing. We approached this problem through c...
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A fourteen-year female Jindo dog showing signs of hemoperitoneum was diagnosed with hemangiosarcoma through abdominal radiography and histopathological examination. In the abdominal radiographs, a circular mass was observed on the posterior of the spleen. When the splenic mass was removed via laparotomy, it was spherical, poorly circumscribed, and showed signs of necrosis, with white spots pres...
متن کاملConstitutive expression and roles of interleukin-8 in canine hemangiosarcoma
Results IL-8 mRNA expression was variable among the tissue samples and both IL-8 mRNA and protein were variable among the cell lines. In contrast, IL-8 receptor mRNA and protein showed minimal variance. “IL-8 high” and “IL-8 low” groups were defined from the HSA tumor samples based on gene expression profiles. The “IL-8 high” group was associated with a “reactive microenvironment,” showing enri...
متن کاملComparison of doxorubicin-cyclophosphamide with doxorubicin-dacarbazine for the adjuvant treatment of canine hemangiosarcoma.
Canine hemangiosarcoma (HSA) is a neoplasm of vascular endothelial origin that has an aggressive biological behaviour, with less than 10% of dogs alive at 12-months postdiagnosis. Treatment of choice consists of surgery followed by adjuvant doxorubicin-based chemotherapy. We prospectively compared adjuvant doxorubicin and dacarbazine (ADTIC) to a traditional doxorubicin and cyclophosphamide (AC...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 2000
ISSN: 0891-6640,1939-1676
DOI: 10.1111/j.1939-1676.2000.tb02262.x